Interleukin enhancer-binding factor 3 (ILF3) (AA 302-351) antibody

Catalog No. ABIN1453638

The Rabbit Polyclonal anti-Interleukin enhancer-binding factor 3 antibody (ABIN1453638) specifically detects Interleukin enhancer-binding factor 3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) (AA 302-351) antibody (ABIN1453638)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 302-351

Purpose: NF90 Antibody

Specificity: NF90 Polyclonal Antibody detects endogenous levels of NF90 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NF90. AA range:302-351

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details

Target: Interleukin enhancer-binding factor 3 (ILF3)

Alternative Name: NF90

Background:

Synonyms: ILF3, DRBF, MPHOSPH4, NF90, Interleukin enhancer-binding factor 3, Double-stranded RNA-binding protein 76, DRBP76, M-phase phosphoprotein 4, MPP4, Nuclear factor associated with dsRNA, NFAR, Nuclear factor of activated T-cells 90 kDa, NF-AT-90, Translational control protein 80, TCP80

Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014],

Gene Name: ILF3

Protein Name: Interleukin enhancer-binding factor 3

Molecular Weight: 95 kDa

Gene ID: 3609

OMIM: 603182

UniProt: Q12906

Pathways: M Phase