PAX2A antibody (AA 144-193)

Catalog No. ABIN1453737

The Rabbit Polyclonal anti-PAX2A antibody (ABIN1453737) specifically detects PAX2A in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for PAX2A antibody (AA 144-193) (ABIN1453737)

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PAX2A Antibody

Binding Specificity: AA 144-193

Purpose: Pax-2 Antibody

Specificity: Pax-2 Polyclonal Antibody detects endogenous levels of Pax-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Pax-2. AA range:144-193

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PAX2A

Target: PAX2A (Paired Box Gene 2a (PAX2A))

Alternative Name: Pax-2

Background:

Synonyms: PAX2, Paired box protein Pax-2

Background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: PAX2

Protein Name: Paired box protein Pax-2

Molecular Weight: 44 kDa

Gene ID: 5076

OMIM: 167409

UniProt: Q02962

Pathways: Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation