PDGFA antibody (AA 105-154)
Quick Overview for PDGFA antibody (AA 105-154) (ABIN1453749)
Target
See all PDGFA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 105-154
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Purpose
- PDGF-A Antibody
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Specificity
- PDGF-A Polyclonal Antibody detects endogenous levels of PDGF-A protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human PDGF-A. AA range:105-154
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- PDGFA (Platelet Derived Growth Factor A (PDGFA))
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Alternative Name
- PDGF-A
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Background
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Synonyms: PDGFA, PDGF1, Platelet-derived growth factor subunit A, PDGF subunit A, PDGF-1, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha polypeptide
Background: platelet derived growth factor subunit A(PDGFA) Homo sapiens This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Gene Name: PDGFA
Protein Name: Platelet-derived growth factor subunit A
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Molecular Weight
- 24 kDa
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Gene ID
- 5154
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OMIM
- 173430
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UniProt
- P04085
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Target
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