Pepsin A antibody (AA 258-307)

Catalog No. ABIN1453758

The Rabbit Polyclonal anti-Pepsin A antibody (ABIN1453758) specifically detects Pepsin A in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Pepsin A antibody (AA 258-307) (ABIN1453758)

Target: Pepsin A

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pepsin A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Pepsin A Antibody

Binding Specificity: AA 258-307

Purpose: Pepsin A Antibody

Specificity: Pepsin A Polyclonal Antibody detects endogenous levels of Pepsin A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Pepsin A. AA range:258-307

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Pepsin A

Target: Pepsin A

Background:

Synonyms: Pepsin A, PGA3, PGA4, PGA5

Background: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015],

Gene Name: PGA3/PGA4/PGA5

Protein Name: Pepsin A

Molecular Weight: 41 kDa

Gene ID: 5222, 643847

OMIM: 169700

UniProt: P0DJD8