TRAF3 antibody (AA 240-289)

Catalog No. ABIN1454010

The Rabbit Polyclonal anti-TRAF3 antibody (ABIN1454010) specifically detects TRAF3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for TRAF3 antibody (AA 240-289) (ABIN1454010)

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRAF3 Antibody

Binding Specificity: AA 240-289

Purpose: TRAF3 Antibody

Specificity: TRAF3 Polyclonal Antibody detects endogenous levels of TRAF3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human TRAF3. AA range:240-289

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TRAF3

Target: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Alternative Name: TRAF3

Background:

Synonyms: TRAF3, CAP1, CRAF1, TNF receptor-associated factor 3, CAP-1, CD40 receptor-associated factor 1, CRAF1, CD40-binding protein, CD40BP, LMP1-associated protein 1, LAP1

Background: TNF receptor associated factor 3(TRAF3) Homo sapiens The protein encoded byThis gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010],

Gene Name: TRAF3

Protein Name: TNF receptor-associated factor 3

Molecular Weight: 64 kDa

Gene ID: 7187

OMIM: 601896

UniProt: Q13114

Pathways: NF-kappaB Signaling, Apoptosis, TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades