Vitronectin antibody (AA 209-258)

Catalog No. ABIN1454094

Cited in 1 publication. The Rabbit Polyclonal anti-Vitronectin antibody (ABIN1454094) specifically detects Vitronectin in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Vitronectin antibody (AA 209-258) (ABIN1454094)

Target: Vitronectin (VTN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitronectin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Vitronectin Antibody

Binding Specificity: AA 209-258

Purpose: Vitronectin Antibody

Specificity: Vitronectin Polyclonal Antibody detects endogenous levels of Vitronectin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Vitronectin. AA range:209-258

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-Vitronectin antibody (ABIN1454094)

Shin, Lechtenberg, Fujimoto, Yao, Bartra, Plano, Marassi: "Structure of human Vitronectin C-terminal domain and interaction with Yersinia pestis outer membrane protein Ail." in: Science advances, Vol. 5, Issue 9, pp. eaax5068, (2020) (PubMed).

Target Details for Vitronectin

Target: Vitronectin (VTN)

Alternative Name: Vitronectin

Background:

Synonyms: VTN, Vitronectin, VN, S-protein, Serum-spreading factor, V75

Background: The protein encoded byThis gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008],

Gene Name: VTN

Protein Name: Vitronectin

Molecular Weight: 54 kDa

Gene ID: 7448

OMIM: 193190

UniProt: P04004

Pathways: Autophagy, Smooth Muscle Cell Migration