MLL2 antibody (AA 2-14)

Catalog No. ABIN1494780

The Goat Polyclonal anti-MLL2 antibody (ABIN1494780) specifically detects MLL2 in ELISA, IHC (p) and IHC. The antibody is reactive with Human samples.

Quick Overview for MLL2 antibody (AA 2-14) (ABIN1494780)

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This MLL2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)

Product Details anti-MLL2 Antibody

Binding Specificity: AA 2-14

Specificity: Human MLL2. The immunizing peptide was designed from NP_003473.1. Since then the sequence has changed in the databases and currently differs at two locations in NP_003473.3.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide DSQNLAGEDKDSQ-C from the N-terminus of human MLL2 (NP_003473.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MLL2

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Alternative Name: KMT2D / MLL2

Background: Name/Gene ID: KMT2D

Synonyms: KMT2D, AAD10, ALL1-related protein, KABUK1, KMS, Lysine N-methyltransferase 2D, MLL2, Kabuki make-up syndrome, ALR, CAGL114, KMT2B, Lysine N-methyltransferase 2B, TNRC21

Gene ID: 8085

NCBI Accession: NP_003473

UniProt: O14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect