CHRNA5 antibody (AA 23-240)

Catalog No. ABIN3022469

This anti-CHRNA5 antibody is a Rabbit Polyclonal antibody detecting CHRNA5 in WB. Suitable for Human.

Quick Overview for CHRNA5 antibody (AA 23-240) (ABIN3022469)

Target: CHRNA5 (Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRNA5 Antibody

Binding Specificity: AA 23-240

Sequence: RCGLAGAAGG AQRGLSEPSS IAKHEDSLLK DLFQDYERWV RPVEHLNDKI KIKFGLAISQ LVDVDEKNQL MTTNVWLKQE WIDVKLRWNP DDYGGIKVIR VPSDSVWTPD IVLFDNADGR FEGTSTKTVI RYNGTVTWTP PANYKSSCTI DVTFFPFDLQ NCSMKFGSWT YDGSQVDIIL EDQDVDKRDF FDNGEWEIVS ATGSKGNRTD SCCWYPYV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-240 of human CHRNA5 (NP_000736.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNA5

Target: CHRNA5 (Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5))

Alternative Name: CHRNA5

Background: The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).,CHRNA5,LNCR2,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNA5

Molecular Weight: 53 kDa

Gene ID: 1138

UniProt: P30532