Tyrosine Hydroxylase antibody (pSer18)

Catalog No. ABIN1531205

This anti-Tyrosine Hydroxylase antibody is a Rabbit Polyclonal antibody detecting Tyrosine Hydroxylase in WB, IHC, IF and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for Tyrosine Hydroxylase antibody (pSer18) (ABIN1531205)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-Tyrosine Hydroxylase Antibody

Binding Specificity: AA 10-59, pSer18

Specificity:

Tyr Hydroxylase (Phospho-Ser19) Antibody detects endogenous levels of Tyr Hydroxylase only when phosphorylated at Ser19.

PhosphorylationH:S18 M:S19 R:S19

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Ser19.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000

Comment:

Unigene-Number: Hs.435609, Hs.523414 (NCBI Gene Symbol: TH)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Synonyms: TH isoform 3, TH isoform a, TH-4, TY3H, TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase, tyrosine hydroxylase

NCBI Gene Symbol: TH

Molecular Weight: 58 kDa

Gene ID: 7054

OMIM: 191290

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour