Tyrosine Hydroxylase antibody (pSer71)

Catalog No. ABIN1531207

The Rabbit Polyclonal anti-Tyrosine Hydroxylase antibody has been validated for WB, IHC and ELISA. It is suitable to detect Tyrosine Hydroxylase in samples from Human, Rat and Mouse.

Quick Overview for Tyrosine Hydroxylase antibody (pSer71) (ABIN1531207)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Tyrosine Hydroxylase Antibody

Binding Specificity: AA 41-90, pSer71

Specificity:

Tyr Hydroxylase (Phospho-Ser40) Antibody detects endogenous levels of Tyr Hydroxylase only when phosphorylated at Ser40.

PhosphorylationH:S71 M:S40 R:S40

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase around the phosphorylation site of Ser40.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.435609, Hs.523414 (NCBI Gene Symbol: TH)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Synonyms: TH isoform 3, TH isoform a, TH-4, TY3H, TYH, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase, tyrosine hydroxylase

NCBI Gene Symbol: TH

Molecular Weight: 58 kDa

Gene ID: 7054

OMIM: 191290

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour