CSK antibody (pSer364)

Catalog No. ABIN1531264

The Rabbit Polyclonal anti-CSK antibody has been validated for WB and ELISA. It is suitable to detect CSK in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for CSK antibody (pSer364) (ABIN1531264)

Target: CSK (C-Src tyrosine Kinase (CSK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CSK Antibody

Binding Specificity: AA 330-379, pSer364

Specificity:

Csk (Phospho-Ser364) Antibody detects endogenous levels of Csk only when phosphorylated at Ser364.

PhosphorylationH:S364 M:S364 R:S364

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Csk around the phosphorylation site of Ser364.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:1000

Comment:

Unigene-Number: Hs.77793 (NCBI Gene Symbol: CSK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

References for anti-CSK antibody (ABIN1531264)

Trepanier, Lei, Xie, MacDonald: "Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase." in: Scientific reports, Vol. 3, pp. 926, (2013) (PubMed).

Target Details for CSK

Target: CSK (C-Src tyrosine Kinase (CSK))

Alternative Name: Csk

Background:

Synonyms: C-SRC kinase, Protein-tyrosine kinase CYL

NCBI Gene Symbol: CSK

Molecular Weight: 50 kDa

Gene ID: 1445

OMIM: 124095

UniProt: P41240

Pathways: TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events