FADD antibody (pSer194)

Catalog No. ABIN1531271

Product Details anti-FADD Antibody

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Binding Specificity: AA 159-208, pSer194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FADD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity:

FADD (Phospho-Ser194) Antibody detects endogenous levels of FADD only when phosphorylated at Ser194.

PhosphorylationH:S194

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FADD around the phosphorylation site of Ser194.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.86131 (NCBI Gene Symbol: FADD)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for FADD

Target: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Alternative Name: FADD (FADD Products)

Background:

Synonyms: FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, MORT1

NCBI Gene Symbol: FADD

Molecular Weight: 23 kDa

Gene ID: 8772

OMIM: 602457

UniProt: Q13158

Pathways: Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades