MEF2C antibody (pSer387)

Catalog No. ABIN1531341

This Rabbit Polyclonal antibody specifically detects MEF2C in IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MEF2C antibody (pSer387) (ABIN1531341)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MEF2C Antibody

Binding Specificity: AA 353-402, pSer387

Purpose: MEF-2C (phospho Ser387) Antibody

Specificity: Phospho-MEF-2C (S387) Polyclonal Antibody detects endogenous levels of MEF-2C protein only when phosphorylated at S387.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MEF2C around the phosphorylation site of Ser387. AA range:353-402

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Background:

Synonyms: MEF2C, Myocyte-specific enhancer factor 2C

Background: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010],

Gene Name: MEF2C

Protein Name: Myocyte-specific enhancer factor 2C

Molecular Weight: 51 kDa

Gene ID: 4208

OMIM: 600662

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling