Ret Proto-Oncogene antibody (RET) (AA 991-1040)

Details for Product anti-RET Antibody No. ABIN1531387, Supplier: Log in to see
Antigen
  • c-ret
  • cret
  • etID315074.13
  • ret1
  • wu:fd13h01
  • X-ret
  • ret-A
  • xret
  • RET
  • MTC1
  • CDHF12
  • CDHR16
  • HSCR1
  • MEN2A
  • MEN2B
  • PTC
  • RET-ELE1
  • RET51
  • RET9
  • c-Ret
  • ret proto-oncogene receptor tyrosine kinase
  • ret proto-oncogene S homeolog
  • ret proto-oncogene
  • ret
  • ret.S
  • RET
  • Ret
Alternatives
anti-Human Ret Proto-Oncogene antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 991-1040, pTyr1015
48
43
27
26
26
22
17
15
15
13
10
10
8
8
8
8
7
7
7
6
5
5
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
396
134
124
11
3
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
265
132
2
2
1
1
Clonality
Polyclonal
Conjugate
This Ret Proto-Oncogene antibody is un-conjugated
16
15
15
12
10
9
8
8
7
7
7
5
5
5
5
5
5
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
293
160
130
85
65
47
36
13
7
6
6
3
3
1
1
1
Options
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Immunogen The antiserum was produced against synthesized peptide derived from human Ret around the phosphorylation site of Tyr1015.
Isotype IgG
Specificity

Ret (Phospho-Tyr1015) Antibody detects endogenous levels of Ret only when phosphorylated at Tyr1015.

PhosphorylationH:Y1015 M:Y1016 R:Y1017

Purification The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Purity > 95 %
Plasmids, Primers & others Plasmids, Primers & others Ret Proto-Oncogene products on genomics-online (e.g. as negative or positive controls)
Antigen Ret Proto-Oncogene (RET)
Alternative Name Ret (RET Antibody Abstract)
Background

Synonyms: C-ret, kinase Ret, Proto-oncogene ret precursor

NCBI Gene Symbol: RET

Molecular Weight 124 kDa
Gene ID 5979
OMIM 114500
UniProt P07949
Pathways RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
Application Notes WB: 1:500~1:1000 ELISA: 1:1000
Comment

Unigene-Number: Hs.350321 (NCBI Gene Symbol: RET)

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20°C for at least 1 year.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Ret Proto-Oncogene (RET) (AA 991-1040), (pTyr1015) antibody (ABIN1531387) Western blot analysis of extracts from COS7 cells treated with EGF 200ng/ml 30', usin...
Background publications Takahashi, Buma, Iwamoto, Inaguma, Ikeda, Hiai: "Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains." in: Oncogene, Vol. 3, Issue 5, pp. 571-8, 1990 (PubMed).

Takahashi, Buma, Hiai: "Isolation of ret proto-oncogene cDNA with an amino-terminal signal sequence." in: Oncogene, Vol. 4, Issue 6, pp. 805-6, 1989 (PubMed).

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