Rhodopsin antibody (pSer334)

Catalog No. ABIN1531388

The Rabbit Polyclonal anti-Rhodopsin antibody (ABIN1531388) specifically detects Rhodopsin in IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Rhodopsin antibody (pSer334) (ABIN1531388)

Target: Rhodopsin (RHO)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rhodopsin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Rhodopsin Antibody

Binding Specificity: AA 299-348, pSer334

Purpose: Rhodopsin (phospho Ser334) Antibody

Specificity: Phospho-Rhodopsin (S334) Polyclonal Antibody detects endogenous levels of Rhodopsin protein only when phosphorylated at S334.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Rhodopsin around the phosphorylation site of Ser334. AA range:299-348

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Rhodopsin

Target: Rhodopsin (RHO)

Alternative Name: Rhodopsin

Target Type: Chemical

Background:

Synonyms: RHO, OPN2, Rhodopsin, Opsin-2

Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008],

Gene Name: RHO

Protein Name: Rhodopsin

Molecular Weight: 39 kDa

Gene ID: 6010

OMIM: 180380

UniProt: P08100

Pathways: WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction