RYR2 antibody (pSer2808)

Catalog No. ABIN1531389

This Rabbit Polyclonal antibody specifically detects RYR2 in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RYR2 antibody (pSer2808) (ABIN1531389)

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-RYR2 Antibody

Binding Specificity: AA 2774-2823, pSer2808

Specificity:

RyR2 (Phospho-Ser2808) Antibody detects endogenous levels of RyR2 only when phosphorylated at Ser2808.

PhosphorylationH:S2808 M:S2808 R:S2798

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RyR2 around the phosphorylation site of Ser2808.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.109514 (NCBI Gene Symbol: RYR2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RYR2

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Alternative Name: RyR2

Background:

Synonyms: cardiac muscle ryanodine receptor-calcium release channel, cardiac muscle-type ryanodine receptor, ryanodine receptor 2, RYR-2

NCBI Gene Symbol: RYR2

Molecular Weight: 564 kDa

Gene ID: 6262

OMIM: 180902

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction