TEK antibody (pTyr1108)

Catalog No. ABIN1531402

Product Details anti-TEK Antibody

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Binding Specificity: AA 1074-1123, pTyr1108

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity:

TIE2 (Phospho-Tyr1108) Antibody detects endogenous levels of TIE2 only when phosphorylated at Tyr1108.

PhosphorylationH:Y1108 M:Y1106

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TIE2 around the phosphorylation site of Tyr1108.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

Comment:

Unigene-Number: Hs.89640 (NCBI Gene Symbol: TEK)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Alternative Name: TIE2 (TEK Products)

Background:

Synonyms: Tyrosine-protein kinase receptor TIE-2, hTIE2, Tyrosine-protein kinase receptor TEK, p140 TEK, Tunica interna endothelial cell kinase, CD202b antigen

NCBI Gene Symbol: TEK

Molecular Weight: 125 kDa

Gene ID: 7010

OMIM: 600195

UniProt: Q02763

Pathways: RTK Signaling, Growth Factor Binding