Tuberin antibody (pSer939)

Catalog No. ABIN1531407

This Rabbit Polyclonal antibody specifically detects Tuberin in ELISA, WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Tuberin antibody (pSer939) (ABIN1531407)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tuberin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Tuberin Antibody

Binding Specificity: AA 905-954, pSer939

Specificity:

Tuberin/TSC2 (Phospho-Ser939) Antibody detects endogenous levels of Tuberin/TSC2 only when phosphorylated at Ser939.

PhosphorylationH:S939 M:S939 R:S939

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Ser939.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.66196, Hs.90303 (NCBI Gene Symbol: TSC2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Alternative Name: Tuberin/TSC2

Background:

Synonyms: TSC2, tuberous sclerosis 2 gene, Tuberous sclerosis 2 homolog protein, Tuberous sclerosis 2 protein

NCBI Gene Symbol: TSC2

Molecular Weight: 200 kDa

Gene ID: 7249

OMIM: 191092

UniProt: P49815

Pathways: RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus