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CHEK2 antibody (pThr383)

This Rabbit Polyclonal antibody specifically detects CHEK2 in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN1531498
$341.00
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Quick Overview for CHEK2 antibody (pThr383) (ABIN1531498)

Target

See all CHEK2 Antibodies
CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity

  • 258
  • 86
  • 72
  • 16
  • 12
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
Human, Mouse, Rat

Host

  • 236
  • 24
  • 1
Rabbit

Clonality

  • 204
  • 57
Polyclonal

Conjugate

  • 114
  • 13
  • 9
  • 9
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
This CHEK2 antibody is un-conjugated

Application

  • 222
  • 80
  • 79
  • 68
  • 61
  • 55
  • 39
  • 31
  • 30
  • 27
  • 18
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • Binding Specificity

    • 33
    • 26
    • 20
    • 17
    • 16
    • 16
    • 15
    • 15
    • 9
    • 9
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-405, pThr383

    Specificity

    Chk2 (Phospho-Thr383) Antibody detects endogenous levels of Chk2 only when phosphorylated at Thr383.

    PhosphorylationH:T383 M:T387 R:T386

    Purification

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    Purity

    > 95 %

    Immunogen

    The antiserum was produced against synthesized peptide derived from human Chk2 around the phosphorylation site of Thr383.

    Isotype

    IgG
  • Application Notes

    WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:20000

    Comment

    Unigene-Number: Hs.291363, Hs.505297 (NCBI Gene Symbol: CHEK2)

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Stable at -20°C for at least 1 year.

    Expiry Date

    12 months
  • Target

    CHEK2 (Checkpoint Kinase 2 (CHEK2))

    Alternative Name

    Chk2

    Background

    Synonyms: Cds1, CHEK2, CHK2, Chk2, CHK2 checkpoint homolog (S. pombe), kinase Chk2, RAD53

    NCBI Gene Symbol: CHEK2

    Molecular Weight

    60 kDa

    Gene ID

    11200

    OMIM

    176807

    UniProt

    O96017

    Pathways

    p53 Signaling, Apoptosis, Cell Division Cycle
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