CDK7 antibody (pThr170)

Catalog No. ABIN1531552

This Rabbit Polyclonal antibody specifically detects CDK7 in WB, IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDK7 antibody (pThr170) (ABIN1531552)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CDK7 Antibody

Binding Specificity: AA 136-185, pThr170

Specificity:

CDK7 (Phospho-Thr170) Antibody detects endogenous levels of CDK7 only when phosphorylated at Thr170.

PhosphorylationH:T170 M:T170

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CDK7 around the phosphorylation site of Thr170.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.184298 (NCBI Gene Symbol: CDK7)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Alternative Name: CDK7

Background:

Synonyms: 39 kDa protein kinase, CAK, CAK1, CDK-activating kinase, CDKN7, CR4 protein kinase, CRK4, Cell division protein kinase 7, MO15, MPK-7, P39 Mo15, Protein-tyrosine kinase MPK-7, STK1, TFIIH basal complex kinase subunit, kinase Cdk7

NCBI Gene Symbol: CDK7

Molecular Weight: 39 kDa

Gene ID: 1022

OMIM: 601955

UniProt: P50613

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase