GATA2 antibody (pSer401)

Catalog No. ABIN1531600

This Rabbit Polyclonal antibody specifically detects GATA2 in WB and ELISA. It exhibits reactivity toward Human and Monkey.

Quick Overview for GATA2 antibody (pSer401) (ABIN1531600)

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GATA2 Antibody

Binding Specificity: AA 367-416, pSer401

Purpose: GATA-2 (phospho Ser401) Antibody

Specificity: Phospho-GATA-2 (S401) Polyclonal Antibody detects endogenous levels of GATA-2 protein only when phosphorylated at S401.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GATA2 around the phosphorylation site of Ser401. AA range:367-416

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GATA2

Target: GATA2 (GATA Binding Protein 2 (GATA2))

Alternative Name: GATA2

Background:

Synonyms: GATA2, Endothelial transcription factor GATA-2, GATA-binding protein 2

Background: This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],

Gene Name: GATA2

Protein Name: Endothelial transcription factor GATA-2

Molecular Weight: 50 kDa

Gene ID: 2624

OMIM: 137295

UniProt: P23769

Pathways: Stem Cell Maintenance