GATA4 antibody (pSer105)

Catalog No. ABIN1531603

This Rabbit Polyclonal antibody specifically detects GATA4 in ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GATA4 antibody (pSer105) (ABIN1531603)

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GATA4 Antibody

Binding Specificity: AA 71-120, pSer105

Purpose: GATA-4 (phospho Ser105) Antibody

Specificity: Phospho-GATA-4 (S105) Polyclonal Antibody detects endogenous levels of GATA-4 protein only when phosphorylated at S105.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GATA4 around the phosphorylation site of Ser105. AA range:71-120

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GATA4

Target: GATA4 (GATA Binding Protein 4 (GATA4))

Alternative Name: GATA4

Background:

Synonyms: GATA4, Transcription factor GATA-4, GATA-binding factor 4

Background: This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Gene Name: GATA4

Protein Name: Transcription factor GATA-4

Molecular Weight: 44 kDa

Gene ID: 2626

OMIM: 600576

UniProt: P43694

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis