Caspase 1 antibody (pSer376)

Catalog No. ABIN1531644

This anti-Caspase 1 antibody is a Rabbit Polyclonal antibody detecting Caspase 1 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Caspase 1 antibody (pSer376) (ABIN1531644)

Target: Caspase 1 (CASP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Caspase 1 Antibody

Binding Specificity: AA 342-391, pSer376

Specificity:

Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of Caspase 1 only when phosphorylated at Ser376.

PhosphorylationH:S376 M:S374 R:S374

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 1 around the phosphorylation site of Ser376.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.2490 (NCBI Gene Symbol: CASP1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: Caspase 1

Background:

Synonyms: CASP-1, caspase-1, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45

NCBI Gene Symbol: CASP1

Molecular Weight: 29 kDa

Gene ID: 834

OMIM: 147678

UniProt: P29466

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome