IRAK1 antibody (pThr100)

Catalog No. ABIN1531672

This Rabbit Polyclonal antibody specifically detects IRAK1 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IRAK1 antibody (pThr100) (ABIN1531672)

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-IRAK1 Antibody

Binding Specificity: AA 66-115, pThr100

Specificity:

IRAK1 (Phospho-Thr100) Antibody detects endogenous levels of IRAK1 only when phosphorylated at Thr100.

PhosphorylationH:T100 M:T100 R:T100

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr100.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.200716, Hs.522819 (NCBI Gene Symbol: IRAK1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Alternative Name: IRAK1

Background:

Synonyms: IL1RAK, IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase, kinase IRAK1, mPLK

NCBI Gene Symbol: IRAK1

Molecular Weight: 76 kDa

Gene ID: 3654

OMIM: 300283

UniProt: P51617

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades