CSNK2A1/CK II alpha antibody (pTyr255)

Catalog No. ABIN1531734

The Rabbit Polyclonal anti-CSNK2A1/CK II alpha antibody (ABIN1531734) specifically detects CSNK2A1/CK II alpha in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CSNK2A1/CK II alpha antibody (pTyr255) (ABIN1531734)

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK2A1/CK II alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CSNK2A1/CK II alpha Antibody

Binding Specificity: AA 221-270, pTyr255

Purpose: Casein Kinase IIα (phospho Tyr255) Antibody

Specificity: Phospho-Casein Kinase IIα (Y255) Polyclonal Antibody detects endogenous levels of Casein Kinase IIα protein only when phosphorylated at Y255.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255. AA range:221-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Background:

Synonyms: CSNK2A1, CK2A1, Casein kinase II subunit alpha, CK II alpha

Background: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation.The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq, Jul 2014],

Gene Name: CSNK2A1

Protein Name: Casein kinase II subunit alpha

Molecular Weight: 45 kDa

Gene ID: 1457

OMIM: 115440

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interactome