MUC1 antibody (pTyr1229)

Catalog No. ABIN1531735

This Rabbit Polyclonal antibody specifically detects MUC1 in IHC, WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for MUC1 antibody (pTyr1229) (ABIN1531735)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MUC1 Antibody

Binding Specificity: AA 1201-1250, pTyr1229

Specificity:

CD227/MUC1 (Phospho-Tyr1229) Antibody detects endogenous levels of CD227/MUC1 only when phosphorylated at Tyr1229.

PhosphorylationH:Y1229

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CD227/MUC1 around the phosphorylation site of Tyr1229.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.89603 (NCBI Gene Symbol: MUC1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: CD227/MUC1

Background:

Synonyms: Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, EMA, Episialin, H23AG, MUC-1, mucin 1, Mucin 1 precursor, mucin 1, transmembrane, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epi

NCBI Gene Symbol: MUC1

Molecular Weight: 122 kDa

Gene ID: 4582

OMIM: 113720

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling