GFAP antibody (pSer38)

Catalog No. ABIN1531740

The Rabbit Polyclonal anti-GFAP antibody (ABIN1531740) specifically detects GFAP in WB, IHC, IF and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GFAP antibody (pSer38) (ABIN1531740)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-GFAP Antibody

Binding Specificity: AA 11-60, pSer38

Purpose: GFAP (phospho Ser38) Antibody

Specificity: Phospho-GFAP (S38) Polyclonal Antibody detects endogenous levels of GFAP protein only when phosphorylated at S38.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GFAP around the phosphorylation site of Ser38. AA range:11-60

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Alternative Name: GFAP

Background:

Synonyms: GFAP, Glial fibrillary acidic protein, GFAP

Background: This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],

Gene Name: GFAP

Protein Name: Glial fibrillary acidic protein

Molecular Weight: 49 kDa

Gene ID: 2670

OMIM: 137780

UniProt: P14136