Nibrin antibody (pSer278)

Catalog No. ABIN1531747

This Rabbit Polyclonal antibody specifically detects Nibrin in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for Nibrin antibody (pSer278) (ABIN1531747)

Target: Nibrin (NBN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nibrin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Nibrin Antibody

Binding Specificity: AA 251-300, pSer278

Specificity:

Nibrin (Phospho-Ser278) Antibody detects endogenous levels of Nibrin only when phosphorylated at Ser278.

PhosphorylationH:S278

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Nibrin around the phosphorylation site of Ser278.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.492208 (NCBI Gene Symbol: NBN)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Nibrin

Target: Nibrin (NBN)

Alternative Name: Nibrin

Background:

Synonyms: Cell cycle regulatory protein P95, NBN, NBS, NIBRIN, NIJMEGEN BREAKAGE syndrome protein 1, p95-NBS1

NCBI Gene Symbol: NBN

Molecular Weight: 84 kDa

Gene ID: 4683

OMIM: 114480

UniProt: O60934

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response