ATF2 antibody (pThr71)

Catalog No. ABIN1531777

This Rabbit Polyclonal antibody specifically detects ATF2 in WB, IHC, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATF2 antibody (pThr71) (ABIN1531777)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-ATF2 Antibody

Binding Specificity: AA 38-87, pThr71

Specificity:

ATF2 (Phospho-Thr71 or 53) Antibody detects endogenous levels of ATF2 only when phosphorylated at Thr71 or 53.

PhosphorylationH:T71 M:T53 R:T53

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ATF2 around the phosphorylation site of Thr71 or 53.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.592510 (NCBI Gene Symbol: ATF2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF2

Background:

Synonyms: Activating 2, ATF2, cAMP response element binding protein CRE- BP1, CREB2, CREBP1, Cyclic-AMP-dependent ATF-2, HB16, MXBP protein

NCBI Gene Symbol: ATF2

Molecular Weight: 52 kDa

Gene ID: 1386

OMIM: 123811

UniProt: P15336

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades