Merlin antibody (pSer518)

Catalog No. ABIN1531906

This Rabbit Polyclonal antibody specifically detects Merlin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Merlin antibody (pSer518) (ABIN1531906)

Target: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Merlin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Merlin Antibody

Binding Specificity: AA 485-534, pSer518

Specificity:

Merlin (Phospho-Ser518) Antibody detects endogenous levels of Merlin only when phosphorylated at Ser518.

PhosphorylationH:S518 M:S518 R:S514

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Merlin around the phosphorylation site of Ser518.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:4000

Comment:

Unigene-Number: Hs.187898 (NCBI Gene Symbol: NF2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Merlin

Target: Merlin (NF2) (Neurofibromin 2 (NF2))

Alternative Name: Merlin

Background:

Synonyms: MERL, moesin-ezrin-radizin-like protein, neurofibromatosis type 2 gene, neurofibromatosis-2, Neurofibromin 2, NF-2, NF2, SCH, Schwannomerlin, schwannomerlin, Schwannomin

NCBI Gene Symbol: NF2

Molecular Weight: 69 kDa

Gene ID: 4771

OMIM: 101000

UniProt: P35240

Pathways: Cell-Cell Junction Organization