Nibrin antibody (pSer343)

Catalog No. ABIN1531914

The Rabbit Polyclonal anti-Nibrin antibody (ABIN1531914) specifically detects Nibrin in WB and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for Nibrin antibody (pSer343) (ABIN1531914)

Target: Nibrin (NBN)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nibrin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Nibrin Antibody

Binding Specificity: AA 310-359, pSer343

Specificity:

p95/NBS1 (Phospho-Ser343) Antibody detects endogenous levels of p95/NBS1 only when phosphorylated at Ser343.

PhosphorylationH:S343 R:S343

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human p95/NBS1 around the phosphorylation site of Ser343.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:5000

Comment:

Unigene-Number: Hs.492208 (NCBI Gene Symbol: NBN)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Nibrin

Target: Nibrin (NBN)

Alternative Name: p95/NBS1

Background:

Synonyms: Cell cycle regulatory protein P95, NBN, NBS, NIBRIN, NIJMEGEN BREAKAGE syndrome protein 1, p95-NBS1

NCBI Gene Symbol: NBN

Molecular Weight: 84 kDa

Gene ID: 4683

OMIM: 114480

UniProt: O60934

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response