MAP2K4 antibody (pThr261)

Catalog No. ABIN1531968

This anti-MAP2K4 antibody is a Rabbit Polyclonal antibody detecting MAP2K4 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for MAP2K4 antibody (pThr261) (ABIN1531968)

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MAP2K4 Antibody

Binding Specificity: AA 227-276, pThr261

Specificity:

SEK1/MKK4 (Phospho-Thr261) Antibody detects endogenous levels of SEK1/MKK4 only when phosphorylated at Thr261.

PhosphorylationH:T261 M:T259 R:T259

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SEK1/MKK4 around the phosphorylation site of Thr261.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.514681 (NCBI Gene Symbol: MAP2K4)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Alternative Name: SEK1/MKK4

Background:

Synonyms: c-Jun N- terminal kinase kinase 1, C-JUN N-terminal kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 4, JNK activating kinase 1, JNK kinase 1, JNKK, JNKK 1, JNKK1, kinase SEK1, MAP kinase kinase 4, MAP2K4, MAPK/ERK kinase 4, MAPKK

NCBI Gene Symbol: MAP2K4

Molecular Weight: 44 kDa

Gene ID: 6416

OMIM: 601335

UniProt: P45985

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling