Stathmin 1 antibody (pSer15)

Catalog No. ABIN1531981

This Rabbit Polyclonal antibody specifically detects Stathmin 1 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Stathmin 1 antibody (pSer15) (ABIN1531981)

Target: Stathmin 1 (STMN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Stathmin 1 Antibody

Binding Specificity: AA 5-54, pSer15

Purpose: Op18 (phospho Ser16) Antibody

Specificity: Phospho-Op18 (S16) Polyclonal Antibody detects endogenous levels of Op18 protein only when phosphorylated at S16.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Stathmin 1 around the phosphorylation site of Ser15. AA range:5-54

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Stathmin 1

Background:

Synonyms: STMN1, C1orf215, LAP18, OP18, Stathmin, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17

Background: This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],

Gene Name: STMN1

Protein Name: Stathmin

Molecular Weight: 17 kDa

Gene ID: 3925

OMIM: 151442

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics