IRAK1 antibody (pSer376)

Catalog No. ABIN1532050

The Rabbit Polyclonal anti-IRAK1 antibody is suitable to detect IRAK1 in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for IRAK1 antibody (pSer376) (ABIN1532050)

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRAK1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-IRAK1 Antibody

Binding Specificity: AA 342-391, pSer376

Specificity:

IRAK1 (Phospho-Ser376) Antibody detects endogenous levels of IRAK1 only when phosphorylated at Ser376.

PhosphorylationH:S376

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Ser376.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.200716, Hs.522819 (NCBI Gene Symbol: IRAK1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IRAK1

Target: IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))

Alternative Name: IRAK1

Background:

Synonyms: IL1RAK, IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1, Pelle-like protein kinase, kinase IRAK1, mPLK

NCBI Gene Symbol: IRAK1

Molecular Weight: 76 kDa

Gene ID: 3654

OMIM: 300283

UniProt: P51617

Pathways: NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades