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PTK2B antibody (pTyr579)

PTK2B Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1532112
  • Target See all PTK2B Antibodies
    PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
    Binding Specificity
    • 24
    • 21
    • 16
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 545-594, pTyr579
    Reactivity
    • 114
    • 113
    • 95
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 145
    • 13
    • 3
    Rabbit
    Clonality
    • 140
    • 21
    Polyclonal
    Conjugate
    • 75
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This PTK2B antibody is un-conjugated
    Application
    • 123
    • 58
    • 43
    • 40
    • 39
    • 26
    • 13
    • 13
    • 9
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity

    PYK2 (Phospho-Tyr579) Antibody detects endogenous levels of PYK2 only when phosphorylated at Tyr579.

    PhosphorylationH:Y579 M:Y579 R:Y579

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Purity
    > 95 %
    Immunogen
    The antiserum was produced against synthesized peptide derived from human PYK2 around the phosphorylation site of Tyr579.
    Isotype
    IgG
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    Discover our top product PTK2B Primary Antibody
  • Application Notes
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
    Comment

    Unigene-Number: Hs.491322 (NCBI Gene Symbol: PTK2B)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Stable at -20°C for at least 1 year.
    Expiry Date
    12 months
  • Target
    PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
    Alternative Name
    PYK2 (PTK2B Products)
    Synonyms
    CADTK antibody, CAKB antibody, FADK2 antibody, FAK2 antibody, PKB antibody, PTK antibody, PYK2 antibody, RAFTK antibody, CAKbeta antibody, E430023O05Rik antibody, Raftk antibody, Pyk2 antibody, fak1b antibody, ptk2.2 antibody, ptk2b antibody, si:ch1073-355e8.1 antibody, protein tyrosine kinase 2 beta antibody, PTK2 protein tyrosine kinase 2 beta antibody, protein tyrosine kinase 2aa antibody, PTK2B antibody, Ptk2b antibody, ptk2aa antibody
    Background

    Synonyms: CADTK, CAK beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, FADK 2, FAK2, Focal adhesion kinase 2, kinase Pyk2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, PTK2B, RAFTK, Related adhesion focal tyrosine kinase

    NCBI Gene Symbol: PTK2B

    Molecular Weight
    115 kDa
    Gene ID
    2185
    OMIM
    601212
    UniProt
    Q14289
    Pathways
    EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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