ATRIP antibody (pSer224)

Catalog No. ABIN1532124

This Rabbit Polyclonal antibody specifically detects ATRIP in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATRIP antibody (pSer224) (ABIN1532124)

Target: ATRIP (ATR Interacting Protein (ATRIP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATRIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ATRIP Antibody

Binding Specificity: AA 190-239, pSer224

Purpose: ATRIP (phospho Ser224) Antibody

Specificity: Phospho-ATRIP (S224) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S224.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser224. AA range:190-239

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ATRIP

Target: ATRIP (ATR Interacting Protein (ATRIP))

Alternative Name: ATRIP

Background:

Synonyms: ATRIP, AGS1, ATR-interacting protein, ATM and Rad3-related-interacting protein

Background: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],

Gene Name: ATRIP

Protein Name: ATR-interacting protein

Molecular Weight: 85 kDa

Gene ID: 84126

OMIM: 606605

UniProt: Q8WXE1