MKP-1/2 antibody (pSer296)

Catalog No. ABIN1532154

Product Details anti-MKP-1/2 Antibody

Target: MKP-1/2 (DUSP1/4) (Dual Specificity Phosphatase 1/4 (DUSP1/4))

Binding Specificity: AA 261-310, pSer296

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKP-1/2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity:

MKP-1/2 (Phospho-Ser296/318) Antibody detects endogenous levels of MKP-1/2 only when phosphorylated at Ser296/318.

PhosphorylationH:S296/318 M:S296/322 R:S296/319

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MKP-1/2 around the phosphorylation site of Ser296/318.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.171695, Hs.710943, Hs.417962 (NCBI Gene Symbol: DUS1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MKP-1/2

Target: MKP-1/2 (DUSP1/4) (Dual Specificity Phosphatase 1/4 (DUSP1/4))

Alternative Name: MKP-1/2 (DUSP1/4 Products)

Background:

Synonyms: 3CH134, CL100, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, DUS1, DUSP1, MAP kinase phosphatase-1, MKP1, Protein-tyrosine phosphatase 3CH134, Protein-tyrosine phosphatase CL100, Protein-tyrosine phosphatase ERP, PTPN1

NCBI Gene Symbol: DUS1

Molecular Weight: 39 kDa

Gene ID: 1843, 1846

OMIM: 600714

UniProt: P28562, Q13115