ERBB3 antibody (pTyr1197)

Catalog No. ABIN1532182

The Rabbit Polyclonal anti-ERBB3 antibody (ABIN1532182) specifically detects ERBB3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ERBB3 antibody (pTyr1197) (ABIN1532182)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ERBB3 Antibody

Binding Specificity: AA 1163-1212, pTyr1197

Specificity:

HER3 (Phospho-Tyr1197) Antibody detects endogenous levels of HER3 only when phosphorylated at Tyr1197.

PhosphorylationH:Y1197 M:Y1194 R:Y1194

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human HER3 around the phosphorylation site of Tyr1197.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:40000

Comment:

Unigene-Number: Hs.118681 (NCBI Gene Symbol: ERBB3)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name: HER3

Background:

Synonyms: c-erbB3, ERB3, ERBB3, HER3, kinase ErbB3, Receptor protein-tyrosine kinase erbB-3 precursor, Tyrosine kinase-type cell surface receptor HER3

NCBI Gene Symbol: ERBB3

Molecular Weight: 148 kDa

Gene ID: 2065

OMIM: 190151

UniProt: P21860

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway