Tuberin antibody (pTyr1571)

Catalog No. ABIN1532185

This anti-Tuberin antibody is a Rabbit Polyclonal antibody detecting Tuberin in ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for Tuberin antibody (pTyr1571) (ABIN1532185)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tuberin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Tuberin Antibody

Binding Specificity: AA 1537-1586, pTyr1571

Specificity:

TSC2 (Phospho-Tyr1571) Antibody detects endogenous levels of TSC2 only when phosphorylated at Tyr1571.

PhosphorylationH:Y1571 M:Y1572 R:Y1573

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human TSC2 around the phosphorylation site of Tyr1571.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.66196, Hs.90303 (NCBI Gene Symbol: TSC2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Alternative Name: TSC2

Background:

Synonyms: TSC2, tuberous sclerosis 2 gene, Tuberous sclerosis 2 homolog protein, Tuberous sclerosis 2 protein

NCBI Gene Symbol: TSC2

Molecular Weight: 200 kDa

Gene ID: 7249

OMIM: 191092

UniProt: P49815

Pathways: RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus