PBK antibody (AA 1-50)

Catalog No. ABIN1532473

The Rabbit Polyclonal anti-PBK antibody is suitable to detect PBK in samples from Human and Monkey. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for PBK antibody (AA 1-50) (ABIN1532473)

Target: PBK (PDZ Binding Kinase (PBK))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PBK Antibody

Binding Specificity: AA 1-50

Purpose: PBK Antibody

Specificity: PBK Polyclonal Antibody detects endogenous levels of PBK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PBK/TOPK. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PBK

Target: PBK (PDZ Binding Kinase (PBK))

Alternative Name: PBK/TOPK

Background:

Synonyms: PBK, TOPK, Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, CT84, MAPKK-like protein kinase, Nori-3, PDZ-binding kinase, Spermatogenesis-related protein kinase, SPK, T-LAK cell-originated protein kinas

Background: PDZ binding kinase(PBK) Homo sapiens This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Gene Name: PBK

Protein Name: Lymphokine-activated killer T-cell-originated protein kinase

Molecular Weight: 36 kDa

Gene ID: 55872

OMIM: 611210

UniProt: Q96KB5