Aryl Hydrocarbon Receptor antibody (AA 2-51)

Catalog No. ABIN1532497

The Rabbit Polyclonal anti-Aryl Hydrocarbon Receptor antibody is suitable to detect Aryl Hydrocarbon Receptor in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for Aryl Hydrocarbon Receptor antibody (AA 2-51) (ABIN1532497)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Binding Specificity: AA 2-51

Purpose: Ah Receptor Antibody

Specificity: Ah Receptor Polyclonal Antibody detects endogenous levels of Ah Receptor protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human AhR. AA range:2-51

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: AhR

Background:

Synonyms: AHR, BHLHE76, Aryl hydrocarbon receptor, Ah receptor, AhR, Class E basic helix-loop-helix protein 76, bHLHe76, AHRR, BHLHE77, KIAA1234, Aryl hydrocarbon receptor repressor, AhR repressor, AhRR, Class E basic helix-loop-helix protein 77, bHL

Background: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],

Gene Name: AHR

Protein Name: Aryl hydrocarbon receptor

Molecular Weight: 96 kDa

Gene ID: 196, 57491

OMIM: 600253

UniProt: P35869

Pathways: Regulation of Cell Size