CSNK1A1 antibody (AA 287-336)

Catalog No. ABIN1532765

The Rabbit Polyclonal anti-CSNK1A1 antibody (ABIN1532765) specifically detects CSNK1A1 in WB, ELISA, IF, ICC and IHC (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CSNK1A1 antibody (AA 287-336) (ABIN1532765)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CSNK1A1 Antibody

Binding Specificity: AA 287-336

Purpose: Casein Kinase Iα Antibody

Specificity: Casein Kinase Iα Polyclonal Antibody detects endogenous levels of Casein Kinase Iα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CKI-alpha. AA range:287-336

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: CKI-alpha

Background:

Synonyms: CSNK1A1, Casein kinase I isoform alpha, CKI-alpha, CK1

Background: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma(IKBKG) Homo sapiens This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016],

Gene Name: CSNK1A1

Protein Name: Casein kinase I isoform alpha

Molecular Weight: 38 kDa

OMIM: 600505

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling