BRCA1 antibody (AA 1491-1540)

Catalog No. ABIN1532821

The Rabbit Polyclonal anti-BRCA1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect BRCA1 in samples from Human.

Quick Overview for BRCA1 antibody (AA 1491-1540) (ABIN1532821)

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-BRCA1 Antibody

Binding Specificity: AA 1491-1540

Specificity:

BRCA1 Antibody detects endogenous levels of total BRCA1 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BRCA1.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.194143 (NCBI Gene Symbol: BRCA1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for BRCA1

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name: BRCA1

Background:

Synonyms: BRCA1, Breast cancer type 1 susceptibility protein, familial breast/ovarian cancer gene 1

NCBI Gene Symbol: BRCA1

Molecular Weight: 207 kDa

Gene ID: 672

OMIM: 113705

UniProt: P38398

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus