DAB1 antibody (AA 199-248)

Catalog No. ABIN1532844

This Rabbit Polyclonal antibody specifically detects DAB1 in WB, IF and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DAB1 antibody (AA 199-248) (ABIN1532844)

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-DAB1 Antibody

Binding Specificity: AA 199-248

Purpose: Dab1 Antibody

Specificity: Dab1 Polyclonal Antibody detects endogenous levels of Dab1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Dab1. AA range:199-248

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for DAB1

Target: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Alternative Name: Dab1

Background:

Synonyms: DAB1, Disabled homolog 1

Background: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, andThe protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: DAB1

Protein Name: Disabled homolog 1

Molecular Weight: 59 kDa

Gene ID: 1600

OMIM: 603448

UniProt: O75553