FGFR1OP antibody (AA 341-390)
Quick Overview for FGFR1OP antibody (AA 341-390) (ABIN1533271)
Target
See all FGFR1OP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 341-390
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Purpose
- FOP Antibody
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Specificity
- FOP Polyclonal Antibody detects endogenous levels of FOP protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Purity
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human FGFR1 Oncogene Partner. AA range:341-390
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))
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Alternative Name
- FGFR1 Oncogene Partner
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Background
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Synonyms: FGFR1OP; FOP; FGFR1 oncogene partner
Background: FGFR1 oncogene partner(FGFR1OP) Homo sapiens This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013],
Gene Name: FGFR1OP
Protein Name: FGFR1 oncogene partner
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Molecular Weight
- 43 kDa
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Gene ID
- 11116
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OMIM
- 605392
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UniProt
- O95684
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Pathways
- M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
Target
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