Cytokeratin 5 antibody (AA 541-590)

Catalog No. ABIN1533326

This Rabbit Polyclonal antibody specifically detects Cytokeratin 5 in IHC, WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Cytokeratin 5 antibody (AA 541-590) (ABIN1533326)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Cytokeratin 5 Antibody

Binding Specificity: AA 541-590

Purpose: Cytokeratin 5 Antibody

Specificity: Cytokeratin 5 Polyclonal Antibody detects endogenous levels of Cytokeratin 5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Keratin 5. AA range:541-590

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Alternative Name: Keratin 5

Background:

Synonyms: KRT5, Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, CK-5, Keratin-5, K5, Type-II keratin Kb5

Background: keratin 5(KRT5) Homo sapiens The protein encoded byThis gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],

Gene Name: KRT5

Protein Name: Keratin type II cytoskeletal 5

Molecular Weight: 62 kDa

Gene ID: 3852

OMIM: 131760

UniProt: P13647