TUBB antibody (AA 401-450)

Catalog No. ABIN1533450

This Rabbit Polyclonal antibody specifically detects TUBB in WB, IHC, IF, ELISA and IP. It exhibits reactivity toward Human, Mouse, Rat, Pig, Cow and Fish.

Quick Overview for TUBB antibody (AA 401-450) (ABIN1533450)

Target: TUBB (Tubulin, beta (TUBB))

Reactivity: Human, Mouse, Rat, Pig, Cow, Fish

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Product Details anti-TUBB Antibody

Binding Specificity: AA 401-450

Purpose: Tubulin β Antibody

Specificity: Tubulin β Polyclonal Antibody detects endogenous levels of Tubulin β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tubulin beta. AA range:401-450

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TUBB

Target: TUBB (Tubulin, beta (TUBB))

Alternative Name: Tubulin beta

Background:

Synonyms: TUBB3, TUBB4, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

Background: tubulin beta 3 class III(TUBB3) Homo sapiens This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010],

Gene Name: TUBB3

Protein Name: Tubulin beta-3 chain

Molecular Weight: 50 kDa

Gene ID: 10381

OMIM: 602661

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase