GSC2 antibody (AA 131-180)

Catalog No. ABIN1533500

The Rabbit Polyclonal anti-GSC2 antibody (ABIN1533500) specifically detects GSC2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GSC2 antibody (AA 131-180) (ABIN1533500)

Target: GSC2 (Goosecoid Homeobox 2 (GSC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GSC2 Antibody

Binding Specificity: AA 131-180

Purpose: GSC2 Antibody

Specificity: GSC2 Polyclonal Antibody detects endogenous levels of GSC2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GSC2. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GSC2

Target: GSC2 (Goosecoid Homeobox 2 (GSC2))

Alternative Name: GSC2

Background:

Synonyms: GSC2, GSCL, Homeobox protein goosecoid-2, GSC-2, Homeobox protein goosecoid-like, GSC-L

Background: Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008],

Gene Name: GSC2

Protein Name: Homeobox protein goosecoid-2

Molecular Weight: 21 kDa

Gene ID: 2928

OMIM: 601845

UniProt: O15499