PHF1 antibody (AA 345-394)

Catalog No. ABIN1533502

The Rabbit Polyclonal anti-PHF1 antibody is suitable to detect PHF1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for PHF1 antibody (AA 345-394) (ABIN1533502)

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PHF1 Antibody

Binding Specificity: AA 345-394

Purpose: PHF1 Antibody

Specificity: PHF1 Polyclonal Antibody detects endogenous levels of PHF1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PHF1. AA range:345-394

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PHF1

Target: PHF1 (PHD Finger Protein 1 (PHF1))

Alternative Name: PHF1

Background:

Synonyms: PHF1, PCL1, PHD finger protein 1, Protein PHF1, Polycomb-like protein 1, hPCl1

Background: This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Gene Name: PHF1

Protein Name: PHD finger protein 1

Molecular Weight: 62 kDa

Gene ID: 5252

OMIM: 602881

UniProt: O43189