Adenylate Kinase 1 antibody (AA 101-150)

Catalog No. ABIN1533580

The Rabbit Polyclonal anti-Adenylate Kinase 1 antibody is suitable to detect Adenylate Kinase 1 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for Adenylate Kinase 1 antibody (AA 101-150) (ABIN1533580)

Target: Adenylate Kinase 1 (AK1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylate Kinase 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Adenylate Kinase 1 Antibody

Binding Specificity: AA 101-150

Purpose: AK1 Antibody

Specificity: AK1 Polyclonal Antibody detects endogenous levels of AK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human KAD1 . AA range:101-150

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Adenylate Kinase 1

Target: Adenylate Kinase 1 (AK1)

Background:

Synonyms: AK1, Adenylate kinase isoenzyme 1, AK 1, ATP-AMP transphosphorylase 1, Myokinase

Background: adenylate kinase 1(AK1) Homo sapiens This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

Gene Name: AK1

Protein Name: Adenylate kinase isoenzyme 1

Molecular Weight: 21 kDa

Gene ID: 203

OMIM: 103000

UniProt: P00568

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process